Feline Lymphoma: Causes

kitten

Feline lymphoma is one of the most common forms of cancer in cats and presents in many different forms, but all involve a common cell type from a lymphocyte, which is a type of white blood cell.  These cells are typically found in lymphoid tissues, such as lymph nodes, … [Read more...]

Surgical treatment of mast cell tumors in dogs

Cute Scruffy Dog

Surgical Treatment of Grade I and II Mast Cell Tumors in Dogs Surgery is the treatment of choice for mast cell tumors in dogs.  Most dogs with single grade I mast cell tumors (>90%) and grade II mast cell tumors (approximately 75%) have long survival times after complete … [Read more...]

Mast Cell Tumors in Dogs: Prognosis

sweet dog

A helpful tool in treating pets with cancer is to identify factors that help establish which group of pets with a particular type of cancer are likely to do better or worse with treatment.  Prognostic factors are features of a tumor that have been shown to predict outcome of … [Read more...]

Mast Cell Tumors in Dogs: Role of C-Kit Receptor

beagle

All mast cells require a certain tyrosine kinase receptor called c-kit, which is a protein on the membrane of the cell, to survive.  Another name for c-kit is stem cell factor (SCF) receptor.   SCF is a growth factor for blood cells and therefore stimulates production of … [Read more...]

Mast Cell Tumors in Dogs: Use of Anti-Histamines

cute dog

A veterinarian may recommend treatment with antihistamines for dogs with mast cell tumors.  Mast cells contain many types of substances that have different functions within the body, one of them being histamine.  The use of anti-histamines is recommended to prevent side … [Read more...]

Mast Cell Tumors in Dogs: Staging

golden retriever

Staging of cancer is a process of determining where that cancer exists in the patient.  That process results in a determination of the stage of a cancer, which is a description of the extent of cancer involvement in the patient.  It is an essential part of pretreatment … [Read more...]

Mast Cell Tumors in Dogs: Grading

dog and kid

One of the strongest predictors of behavior of mast cell tumors is the grade of the tumor.  There are 3 grades of mast cell tumors, defined naturally as grade 1, grade 2 or grade 3 depending on a number of factors. The grade of the tumor can only be determined by removal of … [Read more...]

Mast Cell Tumors in Dogs: Diagnosis

vet with microscope

Mast cell tumors are typically diagnosed on the basis of fine-needle aspiration cytology.  Once a mass is determined to be a mast cell tumor cytologically, whether or not additional tests are indicated prior to surgery is dependent on the presence or absence of negative … [Read more...]

Mast Cell Tumors in Dogs

staffordshore bull terrier

Canine mast cell tumors are the most common type of skin tumor in the dog, accounting for 16-21% of skin tumors.  They occur most commonly in older dogs, but can occur in dogs of any age.  Boxers, Boston terriers, Staffordshire bull terriers, Labrador retrievers, golden … [Read more...]

Cancer in Dogs and Cats: Staging with Nuclear Medicine

Maine Coon Cat

Nuclear medicine or scintigraphy is a less common form of diagnostic testing used to screen cancer in dogs and cats. The primary reason is the cost and general availability of these tests.  It involves the use of expensive equipment, along with special requirements regarding … [Read more...]